Monograph

General Information

Subsidy Information and Financing Scheme

MAF

Ambrisentan Tablet 5 mg, 10 mg

Treatment of adults with a confirmed diagnosis of WHO Functional Class II or III pulmonary arterial...

MAFAmbrisentan Tablet 5 mg, 10 mg

Treatment of adults with a confirmed diagnosis of WHO Functional Class II or III pulmonary arterial hypertension (PAH) who have one of the following PAH aetiologies:
• Idiopathic PAH
• Heritable or familial PAH
• PAH associated with connective tissue disease
• Anorexigen-induced PAH
• PAH associated with HIV infection

Drug Guidance for Subsidy

02/09/2024 Endothelin receptor antagonists for treating pulmonary arterial hypertension

The Ministry of Health’s Drug Advisory Committee has recommended:

Ambrisentan 5 mg and 10 mg ...

02/09/2024 Endothelin receptor antagonists for treating pulmonary arterial hypertension

The Ministry of Health’s Drug Advisory Committee has recommended:

Ambrisentan 5 mg and 10 mg tablets for treating adults with a confirmed diagnosis of WHO Functional Class II or III pulmonary arterial hypertension (PAH) who have one of the following PAH aetiologies:
- Idiopathic PAH;
- Heritable or familial PAH;
- PAH associated with connective tissue disease;
- Anorexigen-induced PAH; or
- PAH associated with HIV infection.

Subsidy status

Ambrisentan 5 mg and 10 mg tablets are recommended for inclusion on the Medication Assistance Fund (MAF) for the abovementioned indication.

MAF assistance does not apply to bosentan 62.5 mg and 125 mg tablets, and macitentan 10 mg tablet.

Post Marketing Information

PMG 24/08/2023 Patient Medication Guide: Taking Volibris (ambrisentan): What You Need to Know

General Availability in Public Healthcare Institution
Users are to consult the respective PHIs for actual inventory availability and supply restrictions/consideration

Tablet 5 mg
Changi General Hospital
Ng Teng Fong General Hospital
Singapore General Hospital
Tan Tock Seng Hospital

Tablet 10 mg
Changi General Hospital
National Heart Centre
Ng Teng Fong General Hospital
Singapore General Hospital
Tan Tock Seng Hospital

Registered Product(s) Information

ORAL

Select a brand starting with the letter:

VOLIBRIS FILM-COATED TABLET 10 MG [SIN15094P]
VOLIBRIS FILM-COATED TABLET 5MG [SIN15093P]

Clinical Info
Product Info

Please select a product for clinical info:

VOLIBRIS FILM-COATED TABLET 10 MG [SIN15094P]
VOLIBRIS FILM-COATED TABLET 5MG [SIN15093P]

Please select a Registered Product for product info.