04/01/2022 Review of cancer drugs for previously treated multiple myeloma
The Ministry of Health’s Drug Advisory Committee has recommended:
- Carfilzomib 30 mg powder for solution for infusion;
- Ixazomib 3 mg and 4 mg capsules; and
- Pomalidomide 1 mg, 2 mg, 3 mg and 4 mg capsules
for previously treated multiple myeloma in line with specific clinical criteria.
Carfilzomib, ixazomib and pomalidomide should be used in line with the recommended treatment regimens listed in the Annex.
Subsidy status
RCarfilzomib 30 mg powder for solution for infusion, ixazomib 3 mg and 4 mg capsules and pomalidomide 1 mg, 2 mg, 3 mg and 4 mg capsules are recommended for inclusion on the Medication Assistance Fund (MAF) in line with the abovementioned indication.
RMAF assistance for carfilzomib will be implemented from 4 January 2022. MAF assistance for ixazomib and pomalidomide will be implemented from 1 September 2022.
NRMAF assistance does not apply to daratumumab 100 mg/5 ml and 400 mg/20 ml concentrate for solution for infusion and 1800 mg/15 ml solution for subcutaneous injection when used for previously treated multiple myeloma.
Clinical indications, subsidy class and MediShield Life claim limits for all drugs included in the evaluation are provided in the Annex.