MAFAbemaciclib Tablet 50 mg, 100 mg, 150 mg
1) Abemaciclib in combination with an aromatase inhibitor as initial endocrine-based therapy for HR positive, HER2 negative, advanced or metastatic breast cancer.
Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice.
2) Abemaciclib in combination with fulvestrant for treating HR positive, HER2 negative, advanced or metastatic breast cancer in patients who have received prior endocrine therapy.
Pre/perimenopausal women treated with this combination could also receive a luteinizing hormone-releasing hormone agonist according to local clinical practice.
3) Abemaciclib in combination with endocrine therapy for adjuvant treatment of patients with HR positive, HER2 negative, node-positive early breast cancer at high risk of recurrence. Maximum treatment duration: 2 years.